γ射线辐照大鼠胸腺细胞中膜与核变化的可能关联
Possible association of membrane and nuclear changes in gamma-irradiated rat thymocytes.
作者信息
Zherbin E A, Chukhlovin A B
出版信息
Int J Radiat Biol Relat Stud Phys Chem Med. 1984 Feb;45(2):179-83. doi: 10.1080/09553008414550191.
PMID:6607903
Abstract
gamma-irradiated rat thymocytes were incubated in medium containing fresh rat serum. After 6 hours in culture, an equal dose dependency was noted for nuclear pyknosis and the loss of surface receptors to autologous erythrocytes. Decreased rosette formation preceded the expression of pyknosis. A possible relation between the membrane changes and pyknosis during interphase death of the thymocytes is discussed.
摘要
将经γ射线照射的大鼠胸腺细胞在含有新鲜大鼠血清的培养基中培养。培养6小时后，观察到核固缩以及对自身红细胞表面受体丧失存在同等剂量依赖性。玫瑰花结形成减少先于核固缩的表现。本文讨论了胸腺细胞间期死亡过程中膜变化与核固缩之间可能存在的关系。
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