Adson M A, van Heerden J A, Ilstrup D M
Arch Surg. 1984 May;119(5):609-14. doi: 10.1001/archsurg.1984.01390170103020.
Our initial use of the distal splenorenal shunt (DSRS) in 1973 was fostered by disappointment with the results of so-called total shunts. This selective shunt was, when anatomically feasible, our preferred therapy until 1980, when surgical referral was affected by enthusiasm for sclerotherapy. Our study of 71 DSRSs is uncontrolled because we could not recruit patients for a prospective randomized trial that involved either no treatment of operations that had proven faults. Our experience shows that operative risk (4%) and incidence of postshunt encephalopathy (6%) are low, that the rate of shunt occlusion is acceptable (10%), and that bleeding is as well controlled as with other shunts. Survival rates correlate with the cause of portal hypertension and with hepatic functional reserve. Analysis of the causes of death shows that the natural history of cirrhosis and coexistent disease are major determinants of prognosis.
1973年,我们最初使用远端脾肾分流术(DSRS)是因为对所谓的全分流术的结果感到失望。在解剖学上可行的情况下,这种选择性分流术一直是我们1980年之前首选的治疗方法,直到1980年,硬化疗法的热潮影响了手术转诊。我们对71例DSRS的研究是非对照性的,因为我们无法招募患者进行前瞻性随机试验,该试验要么不进行治疗,要么进行已被证明有缺陷的手术。我们的经验表明,手术风险(4%)和分流术后脑病的发生率(6%)较低,分流闭塞率可以接受(10%),并且出血的控制与其他分流术一样好。生存率与门静脉高压的病因和肝功能储备相关。对死亡原因的分析表明,肝硬化的自然病程和并存疾病是预后的主要决定因素。