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X射线和快中子序贯照射对V79中国仓鼠细胞存活的影响。

The effect of sequential irradiation with X-rays and fast neutrons on the survival of V79 Chinese hamster cells.

作者信息

McNally N J, de Ronde J, Hinchliffe M

出版信息

Int J Radiat Biol Relat Stud Phys Chem Med. 1984 Apr;45(4):301-10. doi: 10.1080/09553008414550441.

DOI:10.1080/09553008414550441
PMID:6609142
Abstract

V79 Chinese hamster cells have been exposed to X-rays or fast neutrons or to the two radiations given sequentially. Cells exposed to a priming dose of X-rays and then exposed immediately to a series of neutron doses regard the X-ray dose as equivalent to a neutron dose giving the same surviving fraction (iso-effective). If the cells are exposed to a neutron dose followed by X-rays the resulting survival is higher than would be obtained if the primary dose had been an iso-effective X-ray dose. However, it is lower than would be expected if the two radiations acted independently. The results imply that there is interaction between the damage caused by X-rays and fast neutrons. If the two radiations are given 3 hours apart they act independently.

摘要

V79中国仓鼠细胞已受到X射线、快中子或这两种辐射的先后照射。先接受一次预照射剂量的X射线,然后立即接受一系列中子剂量照射的细胞,会将X射线剂量视为等同于产生相同存活分数(等效应)的中子剂量。如果细胞先接受中子剂量照射,随后再接受X射线照射,其最终存活率高于以等效应X射线剂量作为初始剂量时的存活率。然而,该存活率低于两种辐射独立作用时预期的存活率。结果表明,X射线和快中子造成的损伤之间存在相互作用。如果两种辐射间隔3小时给予,则它们会独立作用。

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The effect of sequential irradiation with X-rays and fast neutrons on the survival of V79 Chinese hamster cells.X射线和快中子序贯照射对V79中国仓鼠细胞存活的影响。
Int J Radiat Biol Relat Stud Phys Chem Med. 1984 Apr;45(4):301-10. doi: 10.1080/09553008414550441.
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