O'Brien H A, Horton M A
J Clin Pathol. 1984 Jun;37(6):665-8. doi: 10.1136/jcp.37.6.665.
The case of a man with widespread bronchogenic carcinoma associated with pronounced neutrophil leucocytosis is presented. There was no evidence of infection or metastatic bone marrow infiltration. Increased levels of colony stimulating activity were shown in the patient's serum using three methods. Findings in this patient suggest that the leukaemoid blood picture was related to inappropriate tumour associated production of colony stimulating factors.
本文报告一例广泛支气管源性癌伴明显中性粒细胞增多症的男性病例。未发现感染或转移性骨髓浸润的证据。采用三种方法检测显示患者血清中集落刺激活性水平升高。该患者的检查结果提示类白血病血象与肿瘤相关的集落刺激因子产生异常有关。