Vincent P, Dubois G, Leclerc H
Rev Epidemiol Sante Publique. 1983;31(2):199-207.
This epidemiological survey was conducted in the Northern country of France, on 753 communes. Nitrate concentration in drinking water was measured from 1974 to 1976. The mean concentration rates (M.C.R.) calculated for the three years, were under 95 mg/l, and 93% were under 43 mg/l. The association between the M.R.C. and digestive and urinary cancer mortality rates observed in the same area (1968-1975) was studied, using different statistical techniques. No systematic relationship was observed taking into account the site of the tumor and the age and the sex of the subjects. The role of other variables is considered in the discussion: duration of exposure, use of other beverages such alcohol or mineral water. The duration of exposure, use of other beverages such alcohol or mineral water. The authors conclude that drinking water does not seem to play a determinant role in the causation of cancer; relationship, if it exists, it remains to be demonstrated.
这项流行病学调查在法国北部的753个市镇进行。于1974年至1976年期间测量了饮用水中的硝酸盐浓度。这三年计算得出的平均浓度率（M.C.R.）低于95毫克/升，93%低于43毫克/升。运用不同的统计技术，研究了同一地区（1968 - 1975年）观察到的平均浓度率（M.R.C.）与消化和泌尿系统癌症死亡率之间的关联。考虑到肿瘤部位、受试者的年龄和性别，未观察到系统性关系。讨论中考虑了其他变量的作用：暴露持续时间、是否饮用酒精或矿泉水等其他饮料。暴露持续时间、是否饮用酒精或矿泉水等其他饮料。作者得出结论，饮用水似乎在癌症病因中不发挥决定性作用；即便存在关联，也仍有待证实。
