关于与H-2相关的对合成多肽抗原无反应性的体外研究。II. 在对（T，G）-A-L和GAT有反应和无反应的小鼠中诱导抑制细胞；
In vitro studies on H-2 linked unresponsiveness to synthetic polypeptide antigens. II. Induction of suppressor cells in both responsive and unresponsive mice to (T,G)-A-L and GAT;
作者信息
Howie S
出版信息
Immunology. 1977 Mar;32(3):301-8.
Abstract
Antigen-specific T-suppressor cells can be induced in vitro from unprimed lymphoid cells of high responder (C57BL/10) and low responder (B10.Br, B10.A, CBA) mice to (T,G)-A-L and high responder (B10, B10;A) and non-responder (B10.G, DBA/1) mice to GAT10. The suppressor cells induced from high and low or non-responder mice appear identical in efficiency, in the antigen concentration required for induction and in their induction kinetics.
摘要
抗原特异性T抑制细胞可在体外从高反应性（C57BL/10）和低反应性（B10.Br、B10.A、CBA）小鼠的未致敏淋巴细胞诱导产生，针对（T，G）-A-L，以及从高反应性（B10、B10；A）和无反应性（B10.G、DBA/1）小鼠的未致敏淋巴细胞诱导产生，针对GAT10。从高反应性、低反应性或无反应性小鼠诱导产生的抑制细胞在效率、诱导所需的抗原浓度及其诱导动力学方面似乎相同。
相似文献
1
2
3
4
5
6
Different T cell requirements for specific memory induction in normal and xid B cells.正常B细胞和xid B细胞中特定记忆诱导的不同T细胞需求。
J Immunol. 1986 Nov 1;137(9):2796-801.
7
8
9
Peptide vaccines incorporating a 'promiscuous' T-cell epitope bypass certain haplotype restricted immune responses and provide broad spectrum immunogenicity.包含“混杂”T细胞表位的肽疫苗可绕过某些单倍型受限的免疫反应，并提供广谱免疫原性。
J Mol Recognit. 1993 Jun;6(2):81-94. doi: 10.1002/jmr.300060206.
引用本文的文献
1
Polygenic control of the immune response to F antigen.对F抗原免疫反应的多基因控制
Immunogenetics. 1981;12(3-4):237-51. doi: 10.1007/BF01561667.
2
Helper and suppressor T cell factors.辅助性和抑制性T细胞因子。
Springer Semin Immunopathol. 1980 May;3(1):93-127. doi: 10.1007/BF00199927.
3
Antigen-specific T-cell factors.抗原特异性T细胞因子。
Immunology. 1980 Dec;41(4):759-87. doi: 10.1007/BF00199524.
4
Suppressor-cell induction in vitro. IV. Target of antigen-specific suppressor factor and its genetic relationships.体外抑制细胞诱导。IV. 抗原特异性抑制因子的靶标及其遗传关系。
J Exp Med. 1978 Jan 1;147(1):110-22. doi: 10.1084/jem.147.1.110.
本文引用的文献
1
Genetic control of immune responses in vitro. 3. Tolerogenic properties of the terpolymer L-glutamic acid 60-L-alanine30-L-tyrosine10 (GAT) for spleen cells from nonresponder (H-2s and H-2q) mice.体外免疫反应的遗传控制。3. 三元共聚物L-谷氨酸60-L-丙氨酸30-L-酪氨酸10（GAT）对无反应性（H-2s和H-2q）小鼠脾细胞的致耐受性特性。
J Exp Med. 1974 Jul 1;140(1):172-84. doi: 10.1084/jem.140.1.172.
2
A cellular basis for genetically controlled immunologic unresponsiveness in mice: tolerance induction in T-cells.小鼠基因控制的免疫无反应性的细胞基础：T细胞中的耐受性诱导。
Proc Natl Acad Sci U S A. 1973 Jan;70(1):250-4. doi: 10.1073/pnas.70.1.250.
3
Genetic control of immune responses in vitro. II. Cellular requirements for the development of primary plaque-forming cell responses to the random terpolymer 1-glutamic acid 60-1-alanine30-1-tyrosine10 (GAT) by mouse spleen cells in vitro.体外免疫反应的遗传控制。II. 小鼠脾细胞在体外对随机三聚物1-谷氨酸60-1-丙氨酸30-1-酪氨酸10（GAT）产生原发性噬斑形成细胞反应的细胞条件。
J Exp Med. 1973 Nov 1;138(5):1121-32. doi: 10.1084/jem.138.5.1121.
4
Suppressor cell induction in vitro. II. Cellular requirements of suppressor cell induction.体外抑制细胞诱导。II. 抑制细胞诱导的细胞需求。
Eur J Immunol. 1976 Apr;6(4):302-5. doi: 10.1002/eji.1830060413.
5
Suppressor cell induction in vitro. I. Kinetics of induction of antigen-specific suppressor cells.体外抑制细胞诱导。I. 抗原特异性抑制细胞的诱导动力学。
Eur J Immunol. 1976 Apr;6(4):296-301. doi: 10.1002/eji.1830060412.
6
The role of macrophages in the generation of T-helper cells. I. The requirement for macrophages in helper cell induction and characteristics of the macrophage-T cell interaction.巨噬细胞在辅助性T细胞生成中的作用。I. 辅助性细胞诱导中对巨噬细胞的需求以及巨噬细胞与T细胞相互作用的特征。
Cell Immunol. 1975 Oct;19(2):356-67. doi: 10.1016/0008-8749(75)90217-8.
Zotero 插件