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婴儿期急性细支气管炎后2年的呼吸问题

Respiratory problems 2 years after acute bronchiolitis in infancy.

作者信息

Henry R L, Hodges I G, Milner A D, Stokes G M

出版信息

Arch Dis Child. 1983 Sep;58(9):713-6. doi: 10.1136/adc.58.9.713.

Abstract

We assessed the clinical progress of 55 children 2 years after admission to hospital with acute bronchiolitis and performed lung function tests on 40. During the 2 year follow up period 75% of the children had wheezed, 36% had 2 or more lower respiratory symptoms lasting more than 2 weeks, 33% had more than 100 days of lower respiratory symptoms, and 13% were readmitted to hospital with acute respiratory disease. In addition 60% of the children were hyperinflated on lung function tests. Many of the children with hyperinflation at the 2 year assessment had not been hyperinflated 1 year earlier, suggesting variable airways obstruction. Reversibility of airways obstruction was also assessed by response to nebulised salbutamol. Nine children had a fall greater than 15% in airways resistance after salbutamol and these children had the highest baseline airways resistances. Airways resistance was higher in the children with a family history of atopy.

摘要

我们评估了55名因急性细支气管炎入院两年后的儿童的临床进展情况,并对其中40名儿童进行了肺功能测试。在为期两年的随访期内,75%的儿童曾出现喘息,36%的儿童有两种或更多种持续超过两周的下呼吸道症状,33%的儿童下呼吸道症状持续超过100天,13%的儿童因急性呼吸道疾病再次入院。此外,60%的儿童在肺功能测试中出现肺过度充气。在两年评估时出现肺过度充气的许多儿童在一年前并未出现这种情况,这表明存在可变的气道阻塞。还通过对雾化沙丁胺醇的反应评估气道阻塞的可逆性。9名儿童在使用沙丁胺醇后气道阻力下降超过15%,这些儿童的基线气道阻力最高。有特应性家族史的儿童气道阻力更高。

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