Hodges I G, Groggins R C, Milner A D, Stokes G M
Arch Dis Child. 1981 Sep;56(9):729-32. doi: 10.1136/adc.56.9.729.
Airways obstruction was measured before and after inhaled ipratropium bromide in 32 wheezy children aged between 3 months and 2 years 8 months using a total body plethysmograph and a modification of the forced oscillation technique. No relationship was found between age and incidence of response. About 40% of those under age 18 months had an improvement in lung function. This form of treatment may have a place in the management of the wheezy infant too young to respond to beta-2 stimulants.
采用全身体积描记法和改良强迫振荡技术,对32名年龄在3个月至2岁8个月之间的喘息儿童在吸入异丙托溴铵前后进行气道阻塞测量。未发现年龄与反应发生率之间存在关联。18个月以下儿童中约40%的肺功能有改善。这种治疗方式在治疗太小而无法对β-2激动剂产生反应的喘息婴儿方面可能有一席之地。