Wilson J H, Haalebos M M, Laméris J S, van Urk H, van Esch B
Digestion. 1983;27(2):111-5. doi: 10.1159/000198939.
A 37-year-old woman who presented with systemic lupus erythematosus was found to have a membranous obstruction of the inferior vena cava above the hepatic veins, with an extensive collateral circulation. The obstruction was relieved by a renal vein-right atrial interposition graft, and this was followed by disappearance of the anti-nuclear and anti-DNA antibodies. We postulate that the systemic lupus erythematosus might have been provoked by life-long immune stimulation due to bowel-derived antigens bypassing the hepatic reticuloendothelial system and reaching the systemic circulation, or by immune hyperreactivity associated with the abnormal abdominal venous circulation.
一名37岁患有系统性红斑狼疮的女性被发现肝静脉上方的下腔静脉存在膜性梗阻，并伴有广泛的侧支循环。通过肾静脉 - 右心房搭桥术解除了梗阻，随后抗核抗体和抗DNA抗体消失。我们推测，系统性红斑狼疮可能是由于肠道来源的抗原绕过肝网状内皮系统进入体循环而导致的终身免疫刺激，或者是与异常的腹部静脉循环相关的免疫反应过度所引发的。
