Kubota K, Kumakiri M, Miura Y, Hine K, Kori N, Saito H, Miyazaki K, Arita T
Hokkaido Igaku Zasshi. 1983 Jul;58(4):400-5.
A boric acid and zinc oxide ointment (J.P. VIII) is an unique preparation in Japan, which consist of boric acid (5%), zinc oxide (10%), vegetable oil (usually soybean oil or sesame oil) and yellow wax. The ointment is widely used in the area of Hokkaido, because not only of the customary prescription but also of the characteristic clinical efficiency. However, boric acid has been recognized to be harmful in these days. Therefore, a zinc oxide ointment consisting 10% zinc oxide, soybean oil and white beeswax was tentatively made and evaluated. The zinc oxide ointment presented the same consistency as the boric acid and zinc oxide ointment, measured with penetrometer. The clinical efficiency was also confirmed on six patients with chronic eczema and seven patients with psoriasis vulgaris. The effect on wound healing of the donor site of skin graft was as good as the previous preparation.
硼酸氧化锌软膏（日本药局方第八版）在日本是一种独特的制剂，它由硼酸（5%）、氧化锌（10%）、植物油（通常是大豆油或芝麻油）和黄蜡组成。该软膏在北海道地区广泛使用，不仅因为习惯处方，还因为其独特的临床疗效。然而，近年来硼酸已被认为是有害的。因此，试制并评估了一种由10%氧化锌、大豆油和白蜂蜡组成的氧化锌软膏。用针入度计测量，该氧化锌软膏与硼酸氧化锌软膏具有相同的稠度。对6例慢性湿疹患者和7例寻常型银屑病患者的临床疗效也得到了证实。对皮肤移植供皮区伤口愈合的效果与先前的制剂一样好。
