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[含氧化锌和鱼肝油的软膏剂锌可洁可在伤口愈合动物模型中的作用]

[Effects of the zinc oxide and cod liver oil containing ointment Zincojecol in an animal model of wound healing].

作者信息

Kietzmann M, Braun M

机构信息

Institut für Pharmakologie, Toxikologie und Pharmazie Stiftung Tierärztliche Hochschule Hannover.

出版信息

Dtsch Tierarztl Wochenschr. 2006 Sep;113(9):331-4.

Abstract

The effects of Zincojecol an ointment containing zinc oxide and cod liver oil on wound healing were compared with ointments that either contained no active ingredients or zinc oxide or cod liver oil alone. All formulations enhanced the epidermal proliferation after mechanical irritation of the tail skin. The combination of zinc oxide and cod liver oil was found to be superior to the vehicle control and formulations containing only one active ingredient. This combination was also found to be most efficient in accelerating wound healing being retarded by repeated dexamethasone treatment.

摘要

将含氧化锌和鱼肝油的软膏Zincojecol对伤口愈合的效果与不含活性成分、仅含氧化锌或仅含鱼肝油的软膏进行了比较。所有制剂在机械刺激尾皮肤后均能促进表皮增殖。发现氧化锌和鱼肝油的组合优于赋形剂对照和仅含一种活性成分的制剂。还发现这种组合在加速因反复地塞米松治疗而延迟的伤口愈合方面最有效。

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