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[健康供体与急性呼吸道疾病和支气管炎缓解期频繁患病者免疫参数的相互关系(评估免疫状态的新方法)]

[Interrelation of the immunological parameters of healthy donors and of persons frequently ill with acute respiratory diseases and bronchitis in the remission stage (a new approach to assessing immune status)].

作者信息

Petrov R V, Lebedev K A, Poniakina I D, Petrukhin I S

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1983 Sep(9):99-105.

PMID:6637280
Abstract

The state of the immune system in healthy donors and in chronic bronchitis patients, frequently suffering from acute respiratory diseases, at the period of remission has been studied by the methods of rosette-formation and phagocytosis. The authors propose a new approach to the evaluation of the immune system by regarding each of these groups as a dynamic set of discrete values. As a result, the parameters of the immune system have proved to be interrelated. These interrelations, in contrast to the variability of the numerical values of different parameters, remain constant in health persons and are seemingly the basis of the stability of their internal medium, or at any rate of their immune system. At the same time under the conditions of the remission of chronic bronchitis the interrelation of the above-mentioned parameters has altered in comparison with the normal state, which makes it possible to characterize the immune status of these patients as the state of imbalance of the immune system.

摘要

采用玫瑰花结形成试验和吞噬作用的方法,对健康供血者以及经常患急性呼吸道疾病的慢性支气管炎患者缓解期的免疫系统状况进行了研究。作者提出了一种评估免疫系统的新方法,即将这些组中的每一组视为一组离散值的动态集合。结果表明,免疫系统的参数是相互关联的。与不同参数数值的可变性相反,这些相互关系在健康人身上保持不变,似乎是其体内环境稳定性的基础,或者至少是其免疫系统稳定性的基础。同时,在慢性支气管炎缓解期的情况下,上述参数之间的相互关系与正常状态相比发生了变化,这使得将这些患者的免疫状态描述为免疫系统失衡状态成为可能。

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