Lubman A, Emrick C, Mosimann W F, Freedman R
Drug Alcohol Depend. 1983 Aug;12(1):3-13. doi: 10.1016/0376-8716(83)90049-2.
Affective symptoms were evaluated in chronic alcoholics during a 2-week period following detoxification from alcohol. Increased ratings were apparent both on the Manic State Rating Scale (MSRS) and on the Ma Scale of the Minnesota Multiphasic Personality Inventory (MMPI) in a subgroup of these patients. Primary symptoms included grandiosity, irritability, and mildly increased psychomotor activity. Alcoholics who had been detoxified for several months or hospitalized medical patients did not show similar symptoms. Measurements of urinary 3-methoxy-4-hydroxyphenylethylene glycol (MHPG), a metabolite of norepinephrine which has been associated with manic-depressive illness, also showed increased excretion in a subpopulation of recently detoxified patients. The coexistence of depressed mood in these patients may have led to symptoms of hypomania being previously overlooked, although signs of depression are common in mania itself.
在慢性酒精中毒者戒酒排毒后的2周内，对其情感症状进行了评估。在这些患者的一个亚组中，躁狂状态评定量表（MSRS）和明尼苏达多相人格调查表（MMPI）的Ma量表评分均明显升高。主要症状包括夸大、易怒和轻度的精神运动性活动增加。已经戒酒几个月的酗酒者或住院的内科患者未表现出类似症状。去甲肾上腺素的一种代谢产物——尿3-甲氧基-4-羟基苯乙二醇（MHPG）的测量结果也显示，近期戒酒患者的一个亚群中其排泄量增加。这些患者中同时存在的情绪低落可能导致轻躁狂症状之前被忽视，尽管抑郁症状在躁狂症本身中很常见。
