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The genes coding for the cardiac muscle actin, the skeletal muscle actin and the cytoplasmic beta-actin are located on three different mouse chromosomes.

作者信息

Czosnek H, Nudel U, Mayer Y, Barker P E, Pravtcheva D D, Ruddle F H, Yaffe D

出版信息

EMBO J. 1983;2(11):1977-9. doi: 10.1002/j.1460-2075.1983.tb01687.x.

DOI:10.1002/j.1460-2075.1983.tb01687.x
PMID:6641707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC555396/
Abstract

The actins are a group of highly conserved proteins encoded by a multigene family. We have previously reported that the skeletal muscle actin gene is located on mouse chromosome 3, together with several other unidentified actin DNA sequences. We show here that the gene coding for the cardiac muscle actin, which is closely related to the skeletal muscle actin (1.1% amino acid replacements), is located on mouse chromosome 17. The gene coding for the cytoplasmic beta-actin is located on mouse chromosome 5. Thus, these three actin genes are located on three different chromosomes.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/394e/555396/c4b542b3b313/emboj00264-0120-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/394e/555396/c4b542b3b313/emboj00264-0120-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/394e/555396/c4b542b3b313/emboj00264-0120-a.jpg

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1
The genes coding for the cardiac muscle actin, the skeletal muscle actin and the cytoplasmic beta-actin are located on three different mouse chromosomes.
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2
The genes coding for the muscle contractile proteins, myosin heavy chain, myosin light chain 2, and skeletal muscle actin are located on three different mouse chromosomes.编码肌肉收缩蛋白、肌球蛋白重链、肌球蛋白轻链2和骨骼肌肌动蛋白的基因位于三条不同的小鼠染色体上。
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Proc Natl Acad Sci U S A. 1978 Mar;75(3):1106-10. doi: 10.1073/pnas.75.3.1106.
5
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本文引用的文献

1
The genes coding for the muscle contractile proteins, myosin heavy chain, myosin light chain 2, and skeletal muscle actin are located on three different mouse chromosomes.编码肌肉收缩蛋白、肌球蛋白重链、肌球蛋白轻链2和骨骼肌肌动蛋白的基因位于三条不同的小鼠染色体上。
EMBO J. 1982;1(11):1299-305. doi: 10.1002/j.1460-2075.1982.tb01314.x.
2
A fetal skeletal muscle actin mRNA in the mouse and its identity with cardiac actin mRNA.小鼠胎儿骨骼肌肌动蛋白信使核糖核酸及其与心肌肌动蛋白信使核糖核酸的一致性
Cell. 1982 Aug;30(1):185-92. doi: 10.1016/0092-8674(82)90024-1.
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Molecular structure and evolutionary origin of human cardiac muscle actin gene.
Plant Mol Biol. 1988 Sep;11(5):663-72. doi: 10.1007/BF00017466.
4
Re-localization of Actsk-1 to mouse chromosome 8, a new region of homology with human chromosome 1.Actsk-1重新定位到小鼠8号染色体，这是一个与人类1号染色体新的同源区域。
Mamm Genome. 1993;4(1):15-20. doi: 10.1007/BF00364657.
5
Glutathione S-transferase Ya subunit is coded by a multigene family located on a single mouse chromosome.谷胱甘肽S-转移酶Ya亚基由位于单一小鼠染色体上的一个多基因家族编码。
Nucleic Acids Res. 1984 Jun 25;12(12):4825-33. doi: 10.1093/nar/12.12.4825.
6
A comparison between mammalian and avian fast skeletal muscle alkali myosin light chain genes: regulatory implications.哺乳动物和鸟类快速骨骼肌碱性肌球蛋白轻链基因的比较：调控意义
Nucleic Acids Res. 1985 Jul 11;13(13):4623-43. doi: 10.1093/nar/13.13.4623.
7
The myosin alkali light chain proteins and their genes.肌球蛋白碱性轻链蛋白及其基因。
Biochem J. 1985 Oct 15;231(2):249-61. doi: 10.1042/bj2310249.
8
Genes for skeletal muscle myosin heavy chains are clustered and are not located on the same mouse chromosome as a cardiac myosin heavy chain gene.骨骼肌肌球蛋白重链的基因成簇分布，且与心肌肌球蛋白重链基因不在同一条小鼠染色体上。
Proc Natl Acad Sci U S A. 1985 Nov;82(21):7183-7. doi: 10.1073/pnas.82.21.7183.
9
Upstream regions of the human cardiac actin gene that modulate its transcription in muscle cells: presence of an evolutionarily conserved repeated motif.人类心肌肌动蛋白基因上游区域对其在肌肉细胞中转录的调控：存在一个进化上保守的重复基序。
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10
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Nucleic Acids Res. 1983 Mar 25;11(6):1759-71. doi: 10.1093/nar/11.6.1759.
5
Structure of a human beta-actin-related pseudogene which lacks intervening sequences.一个缺乏间隔序列的人类β-肌动蛋白相关假基因的结构。
Nucleic Acids Res. 1982 Dec 11;10(23):7843-9. doi: 10.1093/nar/10.23.7843.
6
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J Exp Med. 1981 Apr 1;153(4):793-800. doi: 10.1084/jem.153.4.793.
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10
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