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视网膜血管中的单向囊泡运输机制。

Unidirectional vesicular transport mechanism in retinal vessels.

作者信息

Raviola G, Butler J M

出版信息

Invest Ophthalmol Vis Sci. 1983 Nov;24(11):1465-74.

PMID:6642926
Abstract

When horseradish peroxidase (HRP) is introduced into the bloodstream, it is retained in the lumen of the retinal vessels (blood-retina barrier). In this paper, we report that when the same tracer is injected into the vitreous body, it penetrates the lumen of retinal vessels by transcellular vesicular transport. This unidirectional movement of macromolecules out of the eye is not inhibited by ouabain, fluoroacetate, or low temperatures.

摘要

当辣根过氧化物酶(HRP)被引入血液循环时,它会保留在视网膜血管腔(血视网膜屏障)中。在本文中,我们报告称,当将相同的示踪剂注入玻璃体时,它会通过跨细胞囊泡运输穿透视网膜血管腔。这种大分子从眼内的单向移动不受哇巴因、氟乙酸或低温的抑制。

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Unidirectional vesicular transport mechanism in retinal vessels.视网膜血管中的单向囊泡运输机制。
Invest Ophthalmol Vis Sci. 1983 Nov;24(11):1465-74.
2
Unidirectional transport mechanism of horseradish peroxidase in the vessels of the iris.辣根过氧化物酶在虹膜血管中的单向转运机制
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[Basic study on pars plana vitrectomy. Part 2. Electron-microscopic study of the effect on the blood-ocular barrier of the monkey eyes using horseradish peroxidase tracer technique].[玻璃体切除术基础研究。第2部分。利用辣根过氧化物酶示踪技术对猴眼血-眼屏障影响的电子显微镜研究]
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Does unidirectional vesicular transport occur in retinal vessels?单向囊泡运输是否发生在视网膜血管中?
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Ultrastructural studies of the blood-retina barrier after exposure to interleukin-1 beta or tumor necrosis factor-alpha.暴露于白细胞介素-1β或肿瘤坏死因子-α后血视网膜屏障的超微结构研究。
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Ultrastructural analysis of interleukin-1 beta-induced leukocyte recruitment to the rat retina.白细胞介素-1β诱导白细胞募集至大鼠视网膜的超微结构分析
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Roles of inner blood-retinal barrier organic anion transporter 3 in the vitreous/retina-to-blood efflux transport of p-aminohippuric acid, benzylpenicillin, and 6-mercaptopurine.视网膜内血屏障有机阴离子转运体3在对氨基马尿酸、苄青霉素和6-巯基嘌呤从玻璃体/视网膜到血液的外流转运中的作用。
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