Gardiner T A, Archer D B
Br J Ophthalmol. 1986 Apr;70(4):249-54. doi: 10.1136/bjo.70.4.249.
This paper challenges the hypothesis that the smooth 80 nm plasmalemmal caveolae found in abundance at the abluminal aspect of the endothelium in retinal blood vessels participate in a unidirectional vesicular transport mechanism. Evidence is presented which indicates that horseradish peroxidase, when introduced to the extracellular space of the retina via the vitreous body, may enter the intravascular compartment through junctional incompetence which occurs at or after enucleation of the eye. It is proposed that the plasmalemmal caveolae at the abluminal plasma membrane of endothelial cells in retinal blood vessels are static structures which facilitate the transport of small solutes and ions across the blood retinal barrier.
在视网膜血管内皮细胞近腔面大量存在的80纳米光滑质膜小窝参与单向囊泡转运机制。文中给出的证据表明，辣根过氧化物酶经玻璃体引入视网膜细胞外间隙后，可能通过眼球摘除时或摘除后出现的连接缺陷进入血管内间隙。有人提出，视网膜血管内皮细胞近腔质膜上的质膜小窝是静态结构，有助于小溶质和离子跨血视网膜屏障的转运。
