Zahradnik J M, Frank A L, Taber L H
J Clin Microbiol. 1983 Nov;18(5):1266-8. doi: 10.1128/jcm.18.5.1266-1268.1983.
Serum neutralizing antibody and influenza B-specific lymphocyte blast transformation responses were measured in 110 adults and children after an influenza B outbreak. Serum neutralizing antibody and lymphocyte blast transformation responses were seen in 67 to 75% of adults and children recently infected (less than 1 year), but significant lymphocyte blast transformation responses were seen in only 25% of those whose infection was remote (greater than or equal to 3 years). The frequencies of influenza B-induced lymphocyte blast transformation and serum neutralizing antibody responses were similar in the adults and children with similar infection histories.
在一次乙型流感爆发后,对110名成人和儿童进行了血清中和抗体及乙型流感特异性淋巴细胞增殖转化反应检测。近期感染(不到1年)的成人和儿童中,67%至75%出现了血清中和抗体及淋巴细胞增殖转化反应,但感染时间较长(3年及以上)的人群中,只有25%出现了显著的淋巴细胞增殖转化反应。在感染史相似的成人和儿童中,乙型流感诱导的淋巴细胞增殖转化及血清中和抗体反应频率相似。