Acland H M
J Comp Pathol. 1983 Oct;93(4):585-9. doi: 10.1016/0021-9975(83)90065-8.
Chondrosarcomas are rare in cattle and none has been described in detail. A 30 cm diameter chondrosarcoma centred upon the costochondral junctions of the left 9th to 12th ribs of a 5-year-old Aberdeen Angus cow is described. In areas with a cartilaginous matrix the chondrocytes were plump, sometimes binucleate, sometimes bizarre, with occasionally 2 or more cells per lacuna. The other major matrix was loose and fibrillar, and the cells were spindle-shaped or stellate, with a moderate mitotic rate. Small areas appeared fibrosarcomatous. Both major types of matrix were present in the metastases, which extensively involved the pleura, intrathoracic lymph nodes and lungs. Less numerous and smaller metastases were present on the peritoneal surfaces and within several abdominal and pelvic organs. It is postulated that local extension of the tumour from the primary mass was followed by lymphatic spread to the lungs.
软骨肉瘤在牛中很少见，且尚无详细描述。本文描述了一头5岁阿伯丁安格斯母牛左第9至12肋肋软骨交界处有一个直径30厘米的软骨肉瘤。在有软骨基质的区域，软骨细胞饱满，有时双核，有时形态怪异，每个陷窝偶尔有2个或更多细胞。另一种主要基质疏松且呈纤维状，细胞呈梭形或星状，有中度的有丝分裂率。小区域呈纤维肉瘤样。两种主要类型的基质都出现在转移灶中，转移灶广泛累及胸膜、胸内淋巴结和肺。腹膜表面以及几个腹部和盆腔器官内有数量较少且较小的转移灶。据推测，肿瘤从原发肿块局部扩展后，通过淋巴系统扩散至肺部。
