Afra D, Müller W, Slowik F, Wilcke O, Budka H, Turoczy L
Acta Neurochir (Wien). 1983;69(3-4):243-51. doi: 10.1007/BF01401811.
We report 80 supratentorial lobar ependymomas, including 46 recurrences. All underwent operation. In the total collection 34.5% survived for more than 5 years. The behaviour of children and adults was nearly identical. Based on a histological grading into three steps of malignancy (E1, E2, E3), the ependymomas in low grade 1 showed a 5 years' survival time of 41.5%. Compared to a 28.5% survival in group E2 at the same time. Results in group E3, which histologically resembled malignant glioma or glioblastoma, are not relevant because of the small number of cases. More than 50% of the E1 recurrences showed transformation to E2. No transformation into a lower grade of malignancy has been observed.
我们报告了80例幕上叶型室管膜瘤,其中46例复发。所有患者均接受了手术。在全部病例中,34.5%存活超过5年。儿童和成人的情况几乎相同。根据组织学分为三个恶性程度等级(E1、E2、E3),低级别1级的室管膜瘤5年生存率为41.5%。相比之下,E2组同期生存率为28.5%。E3组在组织学上类似于恶性胶质瘤或胶质母细胞瘤,由于病例数少,其结果不具参考价值。超过50%的E1复发表现为向E2转变。未观察到向更低恶性程度的转变。