Guyuron B, Dagys A P, Munro I R, Ross R B
Ann Plast Surg. 1983 Nov;11(5):423-7. doi: 10.1097/00000637-198311000-00010.
This retrospective study is a review of 41 patients who had received irradiation to the head and face during the growth period. Not only is growth of soft tissue and bone of the irradiated area noticeably affected, but other parts of the face can also be involved, especially if the dose is to the upper face and the cranial base. We were able to define a definite cutoff point for a harmful dose for growing facial bones, but the harmful dose for soft tissue could not be determined and may be as low as 400 rads.
这项回顾性研究对41例在生长发育期接受头面部放疗的患者进行了分析。放疗区域的软组织和骨骼生长不仅会受到显著影响，面部其他部位也可能受累，尤其是当放疗剂量作用于上半面部和颅底时。我们能够确定生长中的面部骨骼有害剂量的明确临界点，但软组织的有害剂量无法确定，可能低至400拉德。
