人类癌症基质中肥大细胞数量的减少。
Decrease of mast cells in the stroma of human cancer.
作者信息
Włodarski K, Kukwa A, Blaton O, Dabska M, Ruben R, Borowiecki B, Jeziorny A
出版信息
Arch Immunol Ther Exp (Warsz). 1983;31(2):261-6.
PMID:6651483
Abstract
The number of mast cells in the stroma of human squamous cell cancer -- keratoblastif cum, paraepidermale and male diffusa was 2-30 times lower than in the stroma o-normal squamous epithelium or in the connective tissue distant from neoplastic epithelium. These differences are statistically highly significant. The reduction of mast cel, number apparently might be the result of exhaustion of heparin-containing granules which interfere with tumor growth.
摘要
人鳞状细胞癌——成角质细胞瘤、表皮旁和弥漫性男性癌基质中的肥大细胞数量比正常鳞状上皮基质或远离肿瘤上皮的结缔组织中的低2至30倍。这些差异在统计学上具有高度显著性。肥大细胞数量的减少显然可能是含肝素颗粒耗竭的结果，而这些颗粒会干扰肿瘤生长。
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