Zhuravleva T B, Tumekh I
Arkh Patol. 1993 Mar-Apr;55(2):27-31.
A quantitative histochemical study of 50 cases of laryngeal squamous-cell carcinoma established differences in the structural-metabolic indices characterized by tumour growth and differentiation. Tumor epithelium exhibited lower activity of the aerobic oxidation enzymes and by a lower content of the nuclear nucleic acids. Differentiation of multilayer epithelium of laryngeal mucous membrane in followed by an increase of the histochemical index dispersion. The dispersion of the structural-metabolic indices is decreasing in the tumor epithelium in the process of differentiation and keratinization. The highest degree of anaplasia is observed in the keratinizing form of carcinoma.
对50例喉鳞状细胞癌进行的定量组织化学研究确定了以肿瘤生长和分化为特征的结构代谢指标的差异。肿瘤上皮细胞的需氧氧化酶活性较低，核核酸含量也较低。喉黏膜复层上皮的分化伴随着组织化学指数离散度的增加。在分化和角化过程中，肿瘤上皮细胞的结构代谢指标离散度在降低。在角化型癌中观察到最高程度的间变。
