Martin-Paredero V, Dixon S M, Baker J D, Takiff H, Gomes A S, Busuttil R W, Moore W S
Arch Surg. 1983 Dec;118(12):1417-20. doi: 10.1001/archsurg.1983.01390120045012.
In 400 patients who underwent major aortography, acute renal dysfunction (ARD) occurred in 11.3%. Of the group with normal renal function before the procedure, 8.2% had ARD and 0.8% required dialysis. Patients with prior abnormal renal function had a 41.7% incidence of ARD, and 8.3% required dialysis as a result of angiography. Vigorous intravenous hydration was used in all patients but did not completely prevent renal problems. Two risk factors not previously emphasized were the injection site (higher risk with abdominal aortic studies) and presence of congestive heart failure requiring treatment with digoxin. Other notable risk factors included contrast load and age. These results emphasized that even with modern contrast agents and application of current concepts of treatment, there remains a risk of renal injury with major angiography.
在400例行主动脉造影术的患者中，急性肾功能不全（ARD）的发生率为11.3%。在术前肾功能正常的患者组中，8.2%发生了ARD，0.8%需要透析。既往肾功能异常的患者ARD发生率为41.7%，8.3%因血管造影而需要透析。所有患者均采用了积极的静脉补液，但未能完全预防肾脏问题。两个以前未被强调的危险因素是注射部位（腹主动脉检查风险更高）和存在需要用地高辛治疗的充血性心力衰竭。其他值得注意的危险因素包括造影剂用量和年龄。这些结果强调，即使使用现代造影剂并应用当前的治疗理念，主动脉造影术仍存在肾脏损伤的风险。
