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大鼠眼部组织中的巨噬细胞。局部过敏反应及其他操作后巨噬细胞数量的测定。

Macrophages in ocular tissues of rats. Determination of their number after local anaphylaxis and other procedures.

作者信息

Allansmith M R, Baird R S, Bloch K J

出版信息

Arch Ophthalmol. 1983 Dec;101(12):1930-4. doi: 10.1001/archopht.1983.01040020932021.

Abstract

The number of macrophages in rat ocular tissues was determined, with the tip of the eyelid containing about 3,000 macrophages per cubic millimeter, which is similar to the number of mast cells at this site. Fewer macrophages were present in orbital tissues and conjunctiva. Macrophages accumulated in ocular tissues of immunized rats injected locally with antigen, but the number did not exceed that observed in antigen-injected controls. Injection of various fluids into ocular tissues, but not the trauma of needle punctures alone, stimulated a marked accumulation of macrophages. Thus, the response to nonspecific stimuli masked the macrophage response to antigen-induced, ocular anaphylaxis.

摘要

测定了大鼠眼组织中巨噬细胞的数量,眼睑尖端每立方毫米约含3000个巨噬细胞,这与该部位肥大细胞的数量相似。眼眶组织和结膜中的巨噬细胞较少。在局部注射抗原的免疫大鼠的眼组织中巨噬细胞会聚集,但数量未超过注射抗原的对照中观察到的数量。向眼组织中注射各种液体,而不仅仅是单纯的针刺创伤,会刺激巨噬细胞显著聚集。因此,对非特异性刺激的反应掩盖了巨噬细胞对抗原诱导的眼部过敏反应的反应。

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