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致痫小鼠和正常小鼠大脑中的二价过渡金属离子(Cu2+和Zn2+)

Divalent transition-metal ions (Cu2+ and Zn2+) in the brains of epileptogenic and normal mice.

作者信息

Chung S H, Johnson M S

出版信息

Brain Res. 1983 Dec 5;280(2):323-34. doi: 10.1016/0006-8993(83)90062-8.

Abstract

The concentrations of Cu2+ and Zn2+ in 3 strains of mice were determined spectrophotometrically. The brain of the inborn audiogenic mouse (DBA/2J) contains higher levels of Zn2+ and Cu2+ than those found in the normal mouse (CBA/Ca or Parkes). Small differences in the metallic content in the whole brains of audiogenic and normal mice are accentuated in the hippocampus and the colliculus.

摘要

用分光光度法测定了3株小鼠体内铜离子(Cu2+)和锌离子(Zn2+)的浓度。先天性听源性惊厥小鼠(DBA/2J)大脑中的锌离子和铜离子含量高于正常小鼠(CBA/Ca或帕克斯小鼠)。听源性惊厥小鼠和正常小鼠全脑金属含量的微小差异在海马体和丘脑中更为明显。

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