致聋小鼠和正常小鼠大脑中磷酸吡哆醛水平的测定。
Determination of pyridoxal phosphate levels in the brains of audiogenic and normal mice.
作者信息
Chung S H, Cox R A
出版信息
Neurochem Res. 1983 Oct;8(10):1245-59. doi: 10.1007/BF00963995.
PMID:6656986
Abstract
The concentrations of pyridoxal-5'-phosphate in the brains of audiogenic and normal mice were measured fluorimetrically. The brain of the audiogenic mouse (DBA/2J) contains 25% more pyridoxal-5'-phosphate than the brain of a control mouse. Intraperitoneal injection of this substance causes a transient increase of its concentration in the brain, lasting a few hours. The substance thereafter is degraded to pyridoxal and pyridoxic acid.
摘要
采用荧光法测定了听源性小鼠和正常小鼠大脑中磷酸吡哆醛-5'-磷酸的浓度。听源性小鼠（DBA/2J）大脑中的磷酸吡哆醛-5'-磷酸含量比对照小鼠大脑中的含量高25%。腹腔注射该物质会导致其在大脑中的浓度短暂升高，持续数小时。此后，该物质会降解为吡哆醛和吡哆酸。
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