Marino P, Zanolla L, Nidasio G P, Nicolosi G L, Fabbri A
Eur Heart J. 1983 Oct;4(10):733-7. doi: 10.1093/oxfordjournals.eurheartj.a061387.
The intraobserver, interobserver and beat to beat interpretative reproducibility of two-dimensional echocardiographic images of the mitral valve area has been studied retrospectively in a group of 37 patients affected by rheumatic mitral valve disease. Reproducibility has been expressed either in terms of mean absolute or percent error of duplicate measurements. A group of 11 normal subjects was used for comparison. In our normal group the intraobserver, interobserver and beat to beat reproducibility averaged 1.8 +/- 2.1%, 3.1 +/- 1.4%, 2.7 +/- 2.0% or 0.12 +/- 0.14 cm2, 0.21 +/- 0.10 cm2, 0.17 +/- 0.13 cm2, respectively. In our patient population the intraobserver, interobserver and beat to beat reproducibility averaged 2.7 +/- 2.7% 4.1 +/- 4.9%, 4.6 +/- 3.6% or 0.05 +/- 0.05 cm2, 0.08 +/- 0.10 cm2, 0.08 +/- 0.06 cm2. In both groups there was no statistical difference among intraobserver, interobserver and beat to beat reproducibility either in terms of percent or absolute value. The mean percent error did not significantly differ between normal or stenotic valves or, in this latter group, among valves of different sizes (less than or equal to 1.4 cm2; 1.5-2.4 cm2; greater than or equal to 2.5 cm2). The mean absolute error, on the contrary, statistically differed between the two groups or among valves of different sizes, being larger in normals or in valves greater than or equal to 1.5 cm2. Thus, the interpretative reproducibility for two-dimensional echocardiographic images of the mitral valve area is small and acceptable for most clinical purposes.(ABSTRACT TRUNCATED AT 250 WORDS)
我们对37例风湿性二尖瓣疾病患者进行了回顾性研究，分析二尖瓣区域二维超声心动图图像在观察者内、观察者间以及逐搏解释的可重复性。可重复性通过重复测量的平均绝对误差或百分比误差来表示。选取11名正常受试者作为对照组。在我们的正常组中，观察者内、观察者间以及逐搏的可重复性平均分别为1.8±2.1%、3.1±1.4%、2.7±2.0%，或0.12±0.14平方厘米、0.21±0.10平方厘米、0.17±0.13平方厘米。在我们的患者群体中，观察者内、观察者间以及逐搏的可重复性平均分别为2.7±2.7%、4.1±4.9%、4.6±3.6%，或0.05±0.05平方厘米、0.08±0.10平方厘米、0.08±0.06平方厘米。在两组中，观察者内、观察者间以及逐搏的可重复性在百分比或绝对值方面均无统计学差异。正常瓣膜或狭窄瓣膜之间的平均百分比误差无显著差异，在后者中，不同大小（小于或等于1.4平方厘米；1.5 - 2.4平方厘米；大于或等于2.5平方厘米）的瓣膜之间也无显著差异。相反，平均绝对误差在两组之间或不同大小的瓣膜之间存在统计学差异，在正常瓣膜或大于或等于1.5平方厘米的瓣膜中更大。因此，二尖瓣区域二维超声心动图图像的解释可重复性较小，对于大多数临床目的来说是可以接受的。（摘要截取自250字）
