Zanolla L, Marino P, Nicolosi G L, Peranzoni P F, Poppi A
Chest. 1982 Aug;82(2):154-7. doi: 10.1378/chest.82.2.154.
The effectiveness of two-dimensional echocardiography in assessing mitral valve calcification was compared to radiography of the surgically excised valves in 43 patients affected by rheumatic disease of the mitral valve. Mitral valve calcification was graded as absent or present if single thin or multiple dense conglomerate echoes defined the valvular orifice in short axis view, provided the sensitivity of the instrumentation was adequately optimized. The radiograph of the excised valve was similarly graded. The interobserver reproducibility for both two-dimensional echocardiography and radiography was 100 percent. There were 14 true positives, 19 true negatives, 10 false positives and no false negatives, thus giving, for two-dimensional echocardiography, a sensitivity of 100 percent and a specificity of 65 per cent. It is concluded that two-dimensional echocardiography is an extremely sensitive method for assessing mitral valve calcification, and is prospectively useful also in planning reconstruction versus replacement in mitral valve surgery. Nevertheless, the consistent number of false positives affecting two-dimensional echocardiography represents a definite limit to the specificity of the technique.
在43例二尖瓣风湿性疾病患者中，将二维超声心动图评估二尖瓣钙化的有效性与手术切除瓣膜的X线摄影进行了比较。如果在短轴视图中单个薄回声或多个密集的团块回声界定了瓣膜口，且仪器灵敏度得到充分优化，则二尖瓣钙化分为无或有。切除瓣膜的X线片也进行类似分级。二维超声心动图和X线摄影的观察者间再现性均为100%。有14个真阳性、19个真阴性、10个假阳性且无假阴性，因此二维超声心动图的灵敏度为100%，特异性为65%。结论是二维超声心动图是评估二尖瓣钙化的极其敏感的方法，并且在二尖瓣手术中规划重建与置换方面也具有前瞻性用途。然而，影响二维超声心动图的假阳性数量一致，这对该技术的特异性构成了明确限制。
