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Coumarin toxicity in different strains of mice.

作者信息

Endell W, Seidel G

出版信息

Agents Actions. 1978 Apr;8(3):299-302. doi: 10.1007/BF01966619.

DOI:10.1007/BF01966619
PMID:665441
Abstract

The general toxic effects of coumarin, as well as coumarin hepatotoxicity were found to be less in DBA/2J mice than in CH3/HeJ mice. These results are discussed in the context of a strain-specific coumarin metabolism and indicate the need for suitable animal models to assess the toxicity of a given substance in man.

摘要

相似文献

1
Coumarin toxicity in different strains of mice.
Agents Actions. 1978 Apr;8(3):299-302. doi: 10.1007/BF01966619.
2
Strain-specific enhancement or inhibition of coumarin hepatotoxicity in mice following pretreatment with two different liver enzyme-inducing agents.
Fundam Appl Toxicol. 1996 Nov;34(1):47-55. doi: 10.1006/faat.1996.0174.
3
[Effect of coumarin on the livers of DBA/2J and CH3/HeJ mice].
Arzneimittelforschung. 1979;29(8):1134-40.
4
Species differences in the metabolism and hepatotoxicity of coumarin.香豆素代谢及肝毒性的种属差异
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1993 Jan;104(1):1-8. doi: 10.1016/0742-8413(93)90102-q.
5
[Different enzyme liberation in the liver of rats and mice by a combination of coumarin and rutin sulphate sodium salt (author's transl)].
Arzneimittelforschung. 1977;27(3):617-20.
6
Critical review of the toxicology of coumarin with special reference to interspecies differences in metabolism and hepatotoxic response and their significance to man.
Food Cosmet Toxicol. 1979 Jun;17(3):277-89. doi: 10.1016/0015-6264(79)90289-x.
7
Genetic variation in coumarin hydroxylase activity in the mouse (Mus musculus).小鼠（小家鼠）中香豆素羟化酶活性的遗传变异。
Science. 1974 Aug 16;185(4151):612-4. doi: 10.1126/science.185.4151.612.
8
Studies on the acute effects of coumarin and some coumarin derivatives in the rat.香豆素及某些香豆素衍生物对大鼠的急性作用研究。
Food Chem Toxicol. 1994 Apr;32(4):357-63. doi: 10.1016/0278-6915(94)90074-4.
9
The Hcr (hepatocarcinogen resistance) loci of DBA/2J mice partially suppress phenotypic expression of the Hcs (hepatocarcinogen sensitivity) loci of C3H/HeJ mice.DBA/2J小鼠的Hcr（肝癌致癌物抗性）基因座部分抑制了C3H/HeJ小鼠的Hcs（肝癌致癌物敏感性）基因座的表型表达。
Carcinogenesis. 1995 Aug;16(8):1993-6. doi: 10.1093/carcin/16.8.1993.
10
[Toxicological research and safety consideration of coumarins].香豆素的毒理学研究与安全性考量
Zhongguo Zhong Yao Za Zhi. 2020 Feb;45(3):518-522. doi: 10.19540/j.cnki.cjcmm.20190827.401.

本文引用的文献

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