Yanagisawa K, Hoshina H, Mikuni K, Ichihashi H
Jpn J Antibiot. 1983 Aug;36(8):2201-6.
Clinical studies of cefpiramide (CPM), a newly developed cephem antibiotic, were performed in 10 children with respiratory tract infection in 4 cases, acute enteritis in 2 cases and urinary tract infection in 4 cases aged from 2 months to 10 years and 4 months. CPM was intravenously given to patients at doses of 16 approximately 58 mg/kg/day divided into 3 times for 3 approximately 22 days. Clinical effects were excellent in 6, good in 3 and fair in 1. Bacteriologically, 3 strains of pathogenic organisms (Salmonella C2 group, E. coli and S. faecalis) isolated from the patients were eradicated with the treatment of CPM. No side effect was observed.
对新开发的头孢匹胺（CPM）进行了临床研究，该研究纳入了10名儿童，其中4例患有呼吸道感染，2例患有急性肠炎，4例患有尿路感染，年龄从2个月至10岁4个月。以约16至58mg/kg/天的剂量将CPM静脉注射给患者，分3次给药，持续3至22天。临床效果为6例优秀，3例良好，1例一般。在细菌学方面，从患者中分离出的3株致病生物（沙门氏菌C2组、大肠杆菌和粪肠球菌）经CPM治疗后被根除。未观察到副作用。
