Lal S, Natarajan S, Veliath A J, Garg B R
Lepr India. 1983 Jul;55(3):495-9.
Twenty-five patients of leprosy classified according to the criteria of Ridley and Jopling (1966) were studied to verify the existence of isopathic phenomenon, using lepromin and autoclaved BCG as antigens. BCG as well as lepromin injection sites showed tuberculoid granulomas in all the cases of tuberculoid, borderline tuberculoid, mid-borderline and indeterminate leprosy. In lepromatous and borderline lepromatous cases BCG injection sites showed infiltration of foam cells containing AFB and foci of epithelioid cells, while lepromin injection sites showed infiltration of foam cells containing AFB only. These findings in the present study do not support the occurrence of isopathic phenomenon in leprosy with BCG.
按照里德利和乔普林(1966年)的标准对25例麻风病患者进行了研究,以验证同种病现象的存在,使用麻风菌素和高压灭菌卡介苗作为抗原。在所有结核样型、界线结核样型、中间界线型和未定类麻风病例中,卡介苗以及麻风菌素注射部位均出现结核样肉芽肿。在瘤型和界线类偏瘤型病例中,卡介苗注射部位显示含有抗酸杆菌的泡沫细胞浸润和上皮样细胞灶,而麻风菌素注射部位仅显示含有抗酸杆菌的泡沫细胞浸润。本研究中的这些发现不支持卡介苗在麻风病中出现同种病现象。