Influence of brotizolam on the ventilatory and mouth-occlusion pressure response to hypercapnia in patients with chronic obstructive pulmonary disease.
作者信息
Sybrecht G W
出版信息
Br J Clin Pharmacol. 1983;16 Suppl 2(Suppl 2):425S-430S. doi: 10.1111/j.1365-2125.1983.tb02323.x.
Abstract
Effect of 0.25 mg brotizolam on patients with chronic obstructive lung disease of moderate to severe degree was studied. There was no difference between the slopes of ventilation vs alveolar CO2 for brotizolam and placebo as compared with base line values. Mouth-occlusion pressures did not change under the influence of drug or placebo. Brotizolam (0.25 mg) is without adverse side-effects on respiratory centre output or on mechanics of ventilation.
摘要
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本文引用的文献
1
Nocturnal hypoxemia and associated electrocardiographic changes in patients with chronic obstructive airways disease.
N Engl J Med. 1982 Jan 21;306(3):125-30. doi: 10.1056/NEJM198201213060301.
2
Respiratory disturbances during sleep.睡眠期间的呼吸紊乱。
Clin Chest Med. 1980 Jan;1(1):57-71.
3
A clinical method for assessing the ventilatory response to carbon dioxide.一种评估对二氧化碳通气反应的临床方法。
Australas Ann Med. 1967 Feb;16(1):20-32. doi: 10.1111/imj.1967.16.1.20.
4
Occlusion pressure as a measure of respiratory center output in conscious man.阻塞压作为清醒人体呼吸中枢输出的一种测量方法。
Respir Physiol. 1975 Mar;23(2):181-99. doi: 10.1016/0034-5687(75)90059-6.
5
Mechanical properties of the respiratory system and mouth-occlusion pressure in patients acutely intoxicated with hypnotics.急性催眠药中毒患者呼吸系统的力学特性及口腔闭合压
Lung. 1979;156(1):49-61. doi: 10.1007/BF02713991.
6
Arterial blood gases and pulmonary and systemic arterial pressure during sleep in chronic obstructive pulmonary disease.慢性阻塞性肺疾病患者睡眠期间的动脉血气、肺和体循环动脉压
Sleep. 1978 Winter;1(2):117-24. doi: 10.1093/sleep/1.2.117.
7
Transient hypoxaemia during sleep in chronic bronchitis and emphysema.慢性支气管炎和肺气肿患者睡眠期间的短暂低氧血症。
Lancet. 1979 Jan 6;1(8106):1-4. doi: 10.1016/s0140-6736(79)90451-3.
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