Newman S E
Ann Neurol. 1978 Apr;3(4):299-304. doi: 10.1002/ana.410030404.
Eleven chronic alcoholic patients without other nonneurological or traumatic disease were evaluated by a simultaneous electroencephalogram and computerized axial tomogram. The findings suggested that chronic abusers of approximately 60 years of age or less may have a normal EEG despite the presence of cerebral cortical atrophy or dementia. In alcoholics over 60 years of age, the greater the severity of cerebral cortical atrophy, the greater the slowing in background frequency of the EEG. Voltage diminution and slow-wave transients also occurred more frequently in the older patients. The incidence of EEG abnormalities was greater than the incidence of CAT scan evidence for cerebral cortical atrophy in alcoholics over 60 years of age with dementia.
对11名无其他非神经或创伤性疾病的慢性酒精中毒患者进行了同步脑电图和计算机断层扫描评估。研究结果表明，年龄在60岁及以下的慢性酒精滥用者，尽管存在大脑皮质萎缩或痴呆，脑电图可能仍正常。在60岁以上的酗酒者中，大脑皮质萎缩越严重，脑电图背景频率减慢越明显。老年患者中电压降低和慢波瞬变也更频繁出现。在患有痴呆的60岁以上酗酒者中，脑电图异常的发生率高于计算机断层扫描显示大脑皮质萎缩的发生率。
