Rönty H, Ahonen A, Tolonen U, Heikkilä J, Niemelä O
Department of Neurosurgery, University of Oulu, Finland.
Eur J Clin Invest. 1993 Mar;23(3):182-7. doi: 10.1111/j.1365-2362.1993.tb00759.x.
We report results of clinical examinations, computed tomography, quantitative electroencephalography (QEEG), and cerebral blood flow measurements performed on a series of 56 consecutive brain injury patients including 15 alcohol abusers and 41 non-alcoholic subjects. Greater volumes of intracranial haemorrhage were noted in the alcoholics for a similar severity of injury and local brain atrophy became more pronounced in them during a follow-up of 1 year. After this time, the third ventricle width, distance between frontal horns, the sum of lateral ventricle dimensions and cortical sulci were all markedly larger in the alcoholics. The QEEG results also indicated a weaker improvement in the alcoholics. The cerebral blood flow at the site of the injury was initially slow in the alcoholics when compared to the contralateral region of the other hemisphere, although these differences disappeared during the follow-up. Permanent occupational disability was also found to be associated with pretraumatic alcohol abuse. The findings indicate that ethanol abuse is not only commonly associated with cerebral trauma but is also a risk factor for a more severe brain damage following the injury.
我们报告了对一系列56例连续性脑损伤患者进行临床检查、计算机断层扫描、定量脑电图（QEEG）和脑血流量测量的结果，这些患者包括15名酗酒者和41名非酗酒者。在损伤严重程度相似的情况下，酗酒者颅内出血的量更大，并且在1年的随访期间，他们局部脑萎缩变得更加明显。在这个时间点之后，酗酒者的第三脑室宽度、额角之间的距离、侧脑室尺寸总和以及皮质沟均明显更大。QEEG结果也表明酗酒者的改善较弱。与另一半球的对侧区域相比，酗酒者损伤部位的脑血流量最初较慢，尽管这些差异在随访期间消失了。还发现永久性职业残疾与创伤前酗酒有关。这些发现表明，乙醇滥用不仅通常与脑外伤有关，而且也是损伤后更严重脑损伤的一个危险因素。
