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福斯方D的真菌毒性及其脂质逆转作用。

Fungal toxicity of phosfon D and its reversion by lipids.

作者信息

Vannini G L, Dall'olio G, Donini A

出版信息

Antimicrob Agents Chemother. 1978 Apr;13(4):699-700. doi: 10.1128/AAC.13.4.699.

DOI:10.1128/AAC.13.4.699
PMID:666296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC352313/
Abstract

The growth retardant Phosfon D inhibits the growth of some yeasts and human pathogenic filamentous fungi. The toxic effects of the compound on the dermatophyte Microsporum cookei were completely reversed by adding ergosterol and oleic acid to the medium. The significance of these findings is discussed.

摘要

生长抑制剂福斯方D可抑制某些酵母和人类致病性丝状真菌的生长。通过向培养基中添加麦角固醇和油酸，该化合物对皮肤癣菌库克微孢子菌的毒性作用完全逆转。讨论了这些发现的意义。

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Fungal toxicity of phosfon D and its reversion by lipids.福斯方D的真菌毒性及其脂质逆转作用。
Antimicrob Agents Chemother. 1978 Apr;13(4):699-700. doi: 10.1128/AAC.13.4.699.
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[Fungicidal activity of cyanophytine].
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本文引用的文献

1
Effects of Ancymidol (a Growth Retardant) and Triarimol (a Fungicide) on the Growth, Sterols, and Gibberellins of Phaseolus vulgaris (L.).嘧啶醇（一种生长延缓剂）和三唑醇（一种杀菌剂）对菜豆生长、甾醇和赤霉素的影响
Plant Physiol. 1976 Apr;57(4):640-4. doi: 10.1104/pp.57.4.640.
2
Plant growth retardants as inhibitors of sterol biosynthesis in tobacco seedlings.植物生长延缓剂作为烟草幼苗中甾醇生物合成的抑制剂
Plant Physiol. 1974 Sep;54(3):238-45. doi: 10.1104/pp.54.3.238.
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The free sterols of dermatophytes.
J Invest Dermatol. 1962 Aug;39:91-4. doi: 10.1038/jid.1962.87.
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Effects of inhibitors of sterol synthesis on growth of sordaria and phytophthora.固醇合成抑制剂对粪壳菌和疫霉生长的影响。
J Gen Microbiol. 1969 Jun;56(3):331-43. doi: 10.1099/00221287-56-3-331.
5
Differential inhibition of rat liver cholesterol biosynthesis by plant growth retardants.
Nature. 1970 Mar 28;225(5239):1252-3. doi: 10.1038/2251252a0.
6
Inhibition of ergosterol synthesis in Ustilago maydis by the fungicide triarimol.杀菌剂三唑醇对玉米黑粉菌麦角甾醇合成的抑制作用。
Biochem Biophys Res Commun. 1972 Mar 24;46(6):2048-53. doi: 10.1016/0006-291x(72)90757-7.
7
The effects of a plant-growth retardant, Phosfon, on mammalian lipid metabolism in vivo.
Aust J Biol Sci. 1973 Feb;26(1):113-22.
8
The biogenesis of mitochondria in microorganisms.微生物中线粒体的生物发生
Annu Rev Microbiol. 1972;26:163-98. doi: 10.1146/annurev.mi.26.100172.001115.
9
Effect of pyrimethamine on the morphology and ultrastructure of Saccharomyces cerevisiae.乙胺嘧啶对酿酒酵母形态和超微结构的影响。
Microbios. 1975;12(49):103-9.
10
On the fungitoxicity of some new thiocyanatopyrazole derivatives: electron microscopical study in Trichophyton mentagrophytes.
Mycopathologia. 1976 Jun 4;58(1):39-47. doi: 10.1007/BF00493592.