D'Amelio F E, Kraft L M, D'Amelio E D, Zeman W, Doody L, Pfeffer J, Joyce K, Benton E V
J Hirnforsch. 1983;24(5):479-83.
In the neuropil of layers II and III of the frontal cortex of adult mice, as seen in the electron microscope, sodium pentobarbital anesthesia alone results in a significant decrease in synaptic profile length at 1 day after anesthetization, followed by a return to normal or above normal levels after 2-28 days, while the number of synaptic profiles per unit cross section (profile incidence) is not altered; irradiation with 5-500 rad plateau argon particles significantly inhibits the profile shortening effect of anesthesia at 1 day after exposure, but this inhibition is not dose related; an inverse dose relationship in profile incidence appears at 2 days following irradiation with argon particles; at 1 to 2 hours after 150 or 220 rad x-irradiation, profile incidence is significantly reduced while the length is increased, effects that appear to be dose related and unaffected by adrenalectomy.
在成年小鼠额叶皮质II层和III层的神经毡中，如在电子显微镜下所见，单独使用戊巴比妥钠麻醉会导致麻醉后1天突触轮廓长度显著减少，随后在2 - 28天后恢复到正常或高于正常水平，而每单位横截面积的突触轮廓数量（轮廓发生率）没有改变；用5 - 500拉德的平台氩粒子照射在照射后1天显著抑制麻醉的轮廓缩短效应，但这种抑制与剂量无关；氩粒子照射后2天轮廓发生率出现剂量反比关系；在150或220拉德X射线照射后1至2小时，轮廓发生率显著降低而长度增加，这些效应似乎与剂量有关且不受肾上腺切除术的影响。
