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用高效液相色谱法定量测定过氧化苯甲酰并与碘量法作比较。

Quantitative determination of benzoyl peroxide by high-performance liquid chromatography and comparison to the iodometric method.

作者信息

Gaddipati N, Volpe F, Anthony G

出版信息

J Pharm Sci. 1983 Dec;72(12):1398-400. doi: 10.1002/jps.2600721207.

DOI:10.1002/jps.2600721207
PMID:6663473
Abstract

A selective high-performance liquid chromatographic (HPLC) procedure for the quantitative determination of benzoyl peroxide in pharmaceutical dosage forms is described. Benzoyl peroxide was dissolved or extracted in the presence of an internal standard, acenaphthylene. The specificity of the stability-indicating HPLC and iodometric procedures are presented for benzoyl peroxide.

摘要

本文描述了一种用于定量测定药物剂型中过氧化苯甲酰的选择性高效液相色谱（HPLC）方法。过氧化苯甲酰在萘嵌戊烯作为内标物存在的情况下进行溶解或萃取。文中给出了用于过氧化苯甲酰的稳定性指示HPLC法和碘量法的特异性。

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引用本文的文献

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Proximate composition, functional properties and quantitative analysis of benzoyl peroxide and benzoic acid in wheat flour samples: effect on wheat flour quality.小麦粉样品中过氧化苯甲酰和苯甲酸的近似成分、功能特性及定量分析：对小麦粉品质的影响
PeerJ. 2020 Mar 24;8:e8788. doi: 10.7717/peerj.8788. eCollection 2020.
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A rapid and sensitive spectrophotometric method for the determination of benzoyl peroxide in wheat flour samples.一种快速灵敏的分光光度法用于测定小麦粉样品中的过氧化苯甲酰。
J Food Drug Anal. 2015 Dec;23(4):652-659. doi: 10.1016/j.jfda.2015.03.006. Epub 2015 May 19.