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1976年日本亚急性硬化性全脑炎的流行病学研究。

An epidemiological study of subacute sclerosing panencephalitis in Japan, 1976.

作者信息

Okuno Y, Nakao T, Ishida N, Konno T, Mizutani H, Sato T, Isomura S, Ueda S, Kitamura I, Kaji M

出版信息

Biken J. 1978 Mar;21(A):9-14.

PMID:666722
Abstract

The National Registry for subacute sclerosing panencephalitis (SSPE) of Japan was established in 1976 at the Research Institute for Microbial Diseases, Osaka University, under the auspices of the Ministry of Health and Welfare. By March 1977, forty five clinically confirmed cases of SSPE were reported to the Registry, with onset of symptoms occurring between 1966 and 1976. Histories of measles were available in 42 of these cases. Thirty nine patients with known histories had measles prior to onset of SSPE and 3 had no history of measles illness. Twenty eight (71.7%) of the 39 patients had measles before the age of 2 years. All cases were 1 to 14 years old at the time of onset of SSPE and the mean interval between measles and SSPE was 6.1 years. One of the 3 cases with no history of measles was a recipient of measles killed vaccine, but no case of SSPE was reported among recipients of measles live, attenuated vaccine.

摘要

日本亚急性硬化性全脑炎(SSPE)国家登记处于1976年在厚生省的支持下,在大阪大学微生物病研究所设立。到1977年3月,有45例临床确诊的SSPE病例报告给了该登记处,症状出现时间在1966年至1976年之间。其中42例有麻疹病史。在这39例有已知病史的患者中,39例在SSPE发病前患过麻疹,3例无麻疹病史。39例患者中有28例(71.7%)在2岁前患过麻疹。所有SSPE发病病例年龄在1至14岁之间,麻疹与SSPE之间的平均间隔时间为6.1年。3例无麻疹病史的患者中有1例接种过麻疹灭活疫苗,但麻疹减毒活疫苗接种者中未报告SSPE病例。

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