Zajicek G
Med Hypotheses. 1983 Dec;12(4):369-76. doi: 10.1016/0306-9877(83)90108-1.
The cancer hazard rate (or force of mortality) of all cancer survival curves of the 4th Report on End Results in Cancer, continuously declines. This pattern recurs also in breast cancer patients refusing treatment. The declining hazard rate is most conspicuous in Cancer and much less pronounced in other chronic diseases. In most of them the hazard rate actually increases. Such is obvious in any actuarial life table, in which the rising pattern represents aging and will therefore be denominated herewith as Aging pattern. It accompanies also many chronic diseases e.g. diabetes, following operation for peptic ulcer, young survivors from coronary occlusion, or cirrhosis. The cancer hazard rate exhibits a trend observable during regeneration and is viewed here to reflect a regenerative process operating in cancer which is ascribed to Neoplasia.
《癌症最终结果第四次报告》中所有癌症生存曲线的癌症风险率（或死亡率）持续下降。这种模式在拒绝治疗的乳腺癌患者中也会再次出现。风险率下降在癌症中最为明显，而在其他慢性疾病中则不太显著。在大多数慢性疾病中，风险率实际上是上升的。这在任何精算生命表中都很明显，其中上升模式代表衰老，因此在此将其称为衰老模式。它也伴随着许多慢性疾病，例如糖尿病、消化性溃疡手术后、冠状动脉闭塞后的年轻幸存者或肝硬化患者。癌症风险率在再生过程中呈现出一种可观察到的趋势，在此被视为反映了癌症中发生的一种再生过程，这归因于肿瘤形成。
