Winder A F, Siddiqui A A, Donovan H C
Br J Ophthalmol. 1978 Jun;62(6):414-9. doi: 10.1136/bjo.62.6.414.
Osmolal, electrolyte, and other responses in peripheral blood were recorded after water loading of patients with ocular hypertension and chronic simple glaucoma, and with a small group of younger normal subjects. The osmolal responses of the ocular hypertensive group were significantly greater than for the glaucoma group, and further differences in plasma potassium concentration were also found. Drinking habits may exert a significant influence in ocular hypertension. The relative contributions to the diagnostic category of the variables recorded was evaluated by discriminant analysis, and the application of this retrospective approach to the assessment of new patients is discussed.
记录了高眼压症和慢性单纯性青光眼患者以及一小群年轻正常受试者水负荷后外周血中的渗透压、电解质及其他反应。高眼压症组的渗透压反应显著大于青光眼组,并且还发现了血浆钾浓度的进一步差异。饮酒习惯可能对高眼压症有显著影响。通过判别分析评估所记录变量对诊断类别的相对贡献,并讨论了这种回顾性方法在新患者评估中的应用。