Rosadini G, Consoli D, Ferrillo F, Rodriguez G, Sannita W G, Silvestro C
Neuropsychobiology. 1983;10(2-3):178-82. doi: 10.1159/000118006.
The present study aims at establishing to what extent adaptation phenomena should be taken into consideration for the definition of an independent baseline in sleep research. To this purpose we have studied: (1) a standard battery of neuropsychological test evaluating performance, subjective assessments of moods and sleep quality; (2) classical sleep parameters; (3) data derived from quantitative analysis of sleep EEG. 19 young male volunteers have been recorded for consecutive nights; 7 of them underwent the recordings for 3, 8 for 6 and 4 for 10 nights. Results can be summarized as follows: (A) both interindividual and intraindividual variability show a progressively decreasing trend toward homogeneity for most of the explored parameters; (B) steady state is reached in different times for different groups of parameters; (C) an adequate group homogeneity was achieved from the 5th night onwards. Implications of these data in sleep studies, namely in sleep active drug research are discussed.
本研究旨在确定在睡眠研究中定义独立基线时应在何种程度上考虑适应现象。为此，我们进行了以下研究：（1）一套标准的神经心理学测试，评估表现、情绪主观评估和睡眠质量；（2）经典睡眠参数；（3）从睡眠脑电图定量分析得出的数据。19名年轻男性志愿者连续多晚进行记录；其中7人记录3晚，8人记录6晚，4人记录10晚。结果可总结如下：（A）对于大多数所探究的参数，个体间和个体内的变异性均呈现出逐渐降低并趋于同质的趋势；（B）不同参数组在不同时间达到稳态；（C）从第5晚起实现了足够的组内同质性。讨论了这些数据在睡眠研究中的意义，即在睡眠活性药物研究中的意义。
