在日本人群中发现的一种HLA - D特异性。

An HLA-D specificity found in the Japanese population.

作者信息

Sasazuki T, McMichael A, Payne R, McDevitt H O, Yakura H, Wakisaka A, Aizawa M, Itakura K

出版信息

Tissue Antigens. 1977 Jan;9(1):62-5. doi: 10.1111/j.1399-0039.1977.tb01082.x.

DOI:10.1111/j.1399-0039.1977.tb01082.x

Abstract

A new HLA-D specificity was found in the Japanese population in two different laboratories. Japanese cell YT, found at Stanford, California, was A9,BW22J,CW1 and cell Wa, found at Sapporo, Japan, was A9,BW22J homozygous. They were shown to be HLA-D identical to the homozygous Japanese cell AH which submitted to the VIth International Histocompatibility Testing Workshop (Workshop number 2-001). This specificity was common in the Japanese (gf = 0.089) but completely absent from 62 Caucasians tested. Strong association of this specificity with HLA-BW22J was demonstrated.

摘要

在两个不同实验室中，日本人群体发现了一种新的HLA - D特异性。在加利福尼亚州斯坦福大学发现的日本细胞YT，其HLA型别为A9、BW22J、CW1；在日本札幌发现的细胞Wa是A9、BW22J纯合子。结果显示，它们与提交给第六届国际组织相容性检测研讨会（研讨会编号2 - 001）的纯合日本细胞AH的HLA - D相同。这种特异性在日本人中很常见（基因频率gf = 0.089），但在测试的62名白种人中完全不存在。已证实这种特异性与HLA - BW22J有强关联。