Kang J Y, Ng S K, Guan R
Ann Acad Med Singap. 1983 Oct;12(4):545-7.
An open study was conducted to assess the efficacy of Cimetidine one gram daily in the treatment of peptic ulcer amongst outpatients in Singapore. Forty patients with duodenal ulcer and fourteen patients with gastric ulcer were entered into the study. Ulcer healing was assessed by endoscopy. At six weeks 85% of duodenal ulcers and 64% of gastric ulcers healed. Although the study is uncontrolled the figures suggest that Cimetidine I gram daily is effective in the treatment of duodenal ulcer in Singapore outpatients. The efficacy of Cimetidine in gastric ulcer, however requires further study.
开展了一项开放性研究,以评估每日服用1克西咪替丁对新加坡门诊患者消化性溃疡的治疗效果。40例十二指肠溃疡患者和14例胃溃疡患者纳入该研究。通过内镜检查评估溃疡愈合情况。六周时,85%的十二指肠溃疡和64%的胃溃疡愈合。尽管该研究为非对照研究,但这些数据表明,每日服用1克西咪替丁对新加坡门诊十二指肠溃疡患者有效。然而,西咪替丁对胃溃疡的疗效还需要进一步研究。