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[两性大鼠乙醇偏好形成的特征]

[Characteristics of the formation of an ethanol preference in rats of both sexes].

作者信息

Andronova L M, Kampov-Polevoĭ A B, Barkov N K, Burov Iu V

出版信息

Farmakol Toksikol. 1983 Jan-Feb;46(1):75-8.

PMID:6681779
Abstract

A high level of initial alcoholic motivation in females is associated with a high metabolic rate as regards ethanol and a low one as regards acetaldehyde in the estrus. The diestrus period is little characteristic in this respect. A high level of alcoholic motivation in males is associated with a high metabolic rate of ethanol and a low one of acetaldehyde. The risk of ethanol preference to water formation is 1.5-2 times higher in male rats than in female ones.

摘要

雌性动物初期对酒精的高动机水平与发情期时乙醇的高代谢率以及乙醛的低代谢率相关。在这方面,间情期没有什么显著特征。雄性动物对酒精的高动机水平与乙醇的高代谢率以及乙醛的低代谢率相关。雄性大鼠对乙醇偏好而非水形成的风险比雌性大鼠高1.5至2倍。

相似文献

1
[Characteristics of the formation of an ethanol preference in rats of both sexes].[两性大鼠乙醇偏好形成的特征]
Farmakol Toksikol. 1983 Jan-Feb;46(1):75-8.
2
[Significance of the sex differences of experimental animals for ethanol and acetaldehyde pharmacokinetics].
Farmakol Toksikol. 1982 Sep-Oct;45(5):101-5.
3
[Possibilities for behavior correction in a learned ethanol preference in female and male white rats].[雌性和雄性白鼠习得性乙醇偏好行为矫正的可能性]
Farmakol Toksikol. 1987 Jul-Aug;50(4):55-60.
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Repeated light-dark phase shifts modulate voluntary ethanol intake in male and female high alcohol-drinking (HAD1) rats.反复进行明暗周期转换可调节雄性和雌性高饮酒量(HAD1)大鼠的自愿乙醇摄入量。
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Biull Eksp Biol Med. 1982 Dec;94(12):60-2.
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Sex differences, alcohol dehydrogenase, acetaldehyde burst, and aversion to ethanol in the rat: a systems perspective.大鼠的性别差异、乙醇脱氢酶、乙醛爆发及对乙醇的厌恶:系统视角
Am J Physiol Endocrinol Metab. 2007 Aug;293(2):E531-7. doi: 10.1152/ajpendo.00187.2007. Epub 2007 May 8.
7
Voluntary ethanol consumption decreases after the inactivation of central acetaldehyde by d-penicillamine.用d-青霉胺使中枢乙醛失活后,自愿乙醇消耗量降低。
Behav Brain Res. 2006 Jul 15;171(1):78-86. doi: 10.1016/j.bbr.2006.03.020. Epub 2006 Apr 18.
8
[Self-stimulation characteristics and endogenous ethanol in rats of different sexes].[不同性别的大鼠的自我刺激特征与内源性乙醇]
Biull Eksp Biol Med. 1984 Jun;97(6):688-90.
9
NTP technical report on toxicity studies of urethane in drinking water and urethane in 5% ethanol administered to F344/N rats and B6C3F1 mice.国家毒理学计划关于给F344/N大鼠和B6C3F1小鼠饮用含氨基甲酸乙酯的水以及饮用含5%乙醇的氨基甲酸乙酯的毒性研究技术报告。
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Voluntary ethanol drinking during the first three postnatal weeks in lines of rats selectively bred for divergent ethanol preference.在出生后前三周,对具有不同乙醇偏好的大鼠品系进行自愿乙醇饮用实验。
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