Varma R R, Crumrine P K, Bergman I, Latchaw R E, Price R A, Vries J, Painter M J
Neurology. 1983 Jun;33(6):806-8. doi: 10.1212/wnl.33.6.806.
Three children with cerebral oligodendrogliomas causing partial complex or generalized seizures presented with completely normal neurologic examinations. CT showed low-density, nonenhancing surface lesions. Although these CT features are usually associated with infarcts or cysts, neoplasm was suspected because of irregularity of the margins and erosion of the adjacent inner table of the skull. Oligodendrogliomas often enlarge slowly and may cause seizures years before they produce focal neurologic signs. CT of all children with seizures not responsive to anticonvulsant medication and focal clinical or EEG abnormalities will hasten diagnosis of slowly growing intracranial mass lesions.
三名患有脑少突胶质细胞瘤并引发部分性复杂发作或全身性癫痫的儿童,其神经系统检查结果完全正常。CT显示低密度、无强化的表浅病变。虽然这些CT特征通常与梗死或囊肿有关,但由于边缘不规则以及邻近颅骨内板受侵蚀,怀疑为肿瘤。少突胶质细胞瘤通常生长缓慢,可能在出现局灶性神经体征前数年就引发癫痫。对于所有对抗惊厥药物无反应且有局灶性临床或脑电图异常的癫痫患儿,进行CT检查将有助于快速诊断缓慢生长的颅内占位性病变。