Brunell P A
Semin Perinatol. 1983 Jan;7(1):47-56.
Maternal varicella during pregnancy may have a variety of effects on the fetus and newborn infant. Infection early in pregnancy may result in fetal malformations. Zoster early in life appears to be a sequela of maternal infection at any period during pregnancy. Infants may escape disease, may have mild varicella, or fatal illness following maternal varicella just prior to delivery. The outcome appears to be related to the onset of maternal and newborn illness relative to delivery. A variety of management options are available to the physician. Choices will be dictated by weighing the risks of VZV infection in a particular situation with the risks and benefits of other proposed intervention. In many cases, recommendations must be made on the basis of very limited data. It is hoped that additional information will lead to a more rational approach to VZV infection of the fetus and newborn.
孕期母亲感染水痘可能会对胎儿和新生儿产生多种影响。孕期早期感染可能导致胎儿畸形。生命早期出现的带状疱疹似乎是母亲在孕期任何阶段感染的后遗症。婴儿可能未患疾病，可能患轻度水痘，或在母亲临产前感染水痘后患上致命疾病。其结果似乎与母亲和新生儿疾病相对于分娩的发病时间有关。医生有多种处理方案可供选择。选择将取决于权衡特定情况下水痘带状疱疹病毒（VZV）感染的风险与其他拟采取干预措施的风险和益处。在许多情况下，必须基于非常有限的数据提出建议。希望更多信息将带来一种更合理的方法来应对胎儿和新生儿的VZV感染。
