Lee K, Uchida T, Koshiba K, Shoji K, Egawa S, Fukuda Y
Gan To Kagaku Ryoho. 1983 Jun;10(6):1466-72.
Methylprednisolone was given to 8 patients receiving CDDP-containing chemotherapy. Of 8 patients, 7 patients achieved complete relief of nausea and emesis and 1 patient obtained partial elimination of symptoms. All these patients had consistent history of severe nausea and emesis before the methylpredisolone trial. At present, a potential effect of methylprednisolone on chemotherapy has not been known. In a case of testicular cancer the titer of tumor markers decreased straight on a table of logarithms.
对8例接受含顺铂化疗的患者给予了甲泼尼龙。8例患者中,7例恶心和呕吐完全缓解,1例症状部分消除。所有这些患者在甲泼尼龙试验前均有严重恶心和呕吐的一致病史。目前,甲泼尼龙对化疗的潜在作用尚不清楚。在1例睾丸癌患者中,肿瘤标志物的滴度在对数表上直线下降。