Romero A, Serratosa J, Sacristán A, Ortiz J A
Arzneimittelforschung. 1983;33(7A):1058-60.
A dose of 5 microCi of cytidine diphosphate choline (CDP-choline, citicoline, Somazina) (methyl 14C) was administered to mice. Animals were sacrificed 10 days after administration and their brain and cerebellum isolated for autoradiography and electron microscopy. Sections were prepared in such a manner that a general topographic assignment of radioactivity distribution to different layers and brain structures could be made. Regarding the intracellular distribution of the different cellular types observed, Purkinje's cells exhibited in a density of focus emission higher than the others.
给小鼠注射5微居里的胞苷二磷酸胆碱（CDP-胆碱、胞磷胆碱、索马西纳）（甲基-14C）。给药10天后处死动物，分离其大脑和小脑用于放射自显影和电子显微镜检查。切片制备方式应能对不同脑层和脑结构的放射性分布进行大致的地形学定位。关于所观察到的不同细胞类型的细胞内分布，浦肯野细胞的聚焦发射密度高于其他细胞。
