Agut J, Font E, Sacristán A, Ortiz J A
Arzneimittelforschung. 1983;33(7A):1045-7.
In this work, the bioavailability of the 14C-methyl-labelled cytidine diphosphate choline (CDP-Choline, citicoline, Somazina), has been studied by oral route, leading to the result that it is slowly and completely absorbed, with a very low urinary and fecal elimination, thus producing maintained blood levels. The bioavailability related to oral route compared with intravenous route is practically the same.
在本研究中，通过口服途径对14C-甲基标记的胞苷二磷酸胆碱（CDP-胆碱、胞磷胆碱、索马西纳）的生物利用度进行了研究，结果表明其吸收缓慢且完全，经尿液和粪便排出极少，从而使血液水平得以维持。与静脉注射途径相比，口服途径的生物利用度基本相同。
