Canton J H, Wester P W, Mathijssen-Spiekman E A
Food Chem Toxicol. 1983 Aug;21(4):369-78. doi: 10.1016/0278-6915(83)90090-x.
The toxicity of sodium bromide for freshwater organisms was tested using algae (Scenedesmus pannonicus), crustaceans (Daphnia magna) and fish (Poecilia reticulata and Oryzias latipes). Depending on the species tested, the acute toxicity varied from 44 to 5800 mg Br-/litre (EC50 values) and the No Observed Effect Concentrations (NOEC values) in the long-term tests varied from 7.8 to 250 mg Br-/litre. Bromide ion markedly impaired reproduction in both crustaceans and fish. Histologically no effects were observed in the long-term test with Oryzias, but in the reproduction test with Poecilia, hyperplasia of the thyroid, atrophy and degeneration of the musculature and regressive changes in the female reproductive tract were observed. As a criterion of water quality, 1 mg Br-/litre has been proposed, on the basis of reproductive performance in the Poecilia test. The concentrations found in surface water frequently exceed this value and sometimes reach levels at which acute effects on water organisms can be expected.
使用藻类(潘诺尼亚栅藻)、甲壳类动物(大型溞)和鱼类(网纹花鳉和青鳉)测试了溴化钠对淡水生物的毒性。根据所测试的物种不同,急性毒性(EC50值)在44至5800毫克溴离子/升之间变化,长期测试中的无观察效应浓度(NOEC值)在7.8至250毫克溴离子/升之间变化。溴离子显著损害了甲壳类动物和鱼类的繁殖能力。组织学上,在青鳉的长期测试中未观察到影响,但在网纹花鳉的繁殖测试中,观察到甲状腺增生、肌肉组织萎缩和退化以及雌性生殖道的退行性变化。根据网纹花鳉测试中的繁殖性能,已提出1毫克溴离子/升作为水质标准。地表水中发现的浓度经常超过该值,有时会达到预期对水生生物产生急性影响的水平。